Mibelle Biochemistry Launches CollPerfect P6 for Collagen Synthesis, Dermal Remodeling

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According to the company, the ingredient's unique composition stimulates collagen synthesis and dermal remodeling for a more youthful, radiant appearance.
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Mibelle Biochemistry has launched CollPerfect P6, an encapsulated bioactivating hexapeptide derived from the sequence of human skin type I collagen. According to the company, the ingredient's unique composition stimulates collagen synthesis and dermal remodeling for a more youthful, radiant appearance.

CollPerfect P6 Structure and Function

Delving deeper into the chemistry, as the company explains, CollPerfect P6 (INCI: Collagen Amino Acids (and) Lecithin (and) Maltodextrin (and) Aqua/Water) is a six amino acid peptide that "contains the characteristic triplet sequence Gly-X-Y of the native human skin type I collagen and its most abundant amino acids: Gly-HyP-Lys-Gly-Pro-Lys."

Mibelle Biochemistry adds that using a shorter hexapeptide improves the ingredient's penetration while the presence of Lys (lysine) improves its solubility. Building from this, the peptide is encapsulated in liposomes to ensure stability and delivery, then it is spray granulated onto maltodextrin to ensure a long shelf life.

Key Mechanisms of CollPerfect P6 

CollPerfect P6 has been shown to improve various skin attributes. It acts through key mechanisms including:

  • promoting procollagen I production,
  • boosting hyaluronic acid release,
  • protecting dermal collagen fibers from aging,
  • tightening facial contours and
  • increasing skin elasticity and density.

Product Positioning and Skin Benefits

Based on the described mechanisms, CollPerfect P6 is positioned as a multifunctional that addresses the visible effects of aging at the root level. Indeed, clinical research underscores its efficacy in maintaining elasticity, firmness and a youthful skin structure.

Per the company, the ingredient responds to recent studies suggesting that declining collagen levels might not just be a consequence of aging, but a potential cause.

CollPerfect 6 Properties

The ingredient is provided as a water-soluble powder without alcohol or preservatives. It is recommended at a use level of 2%.

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