9.6 Years Younger in 90 Days? 35 Clinics Confirm RoC 35's THPE + Retinol + HA + Vitamin C-powered Effects

Ro C 35 Pack Shot (1)
RoC

RoC Skincare recently unveiled its groundbreaking skin care protocol, RoC 35, comprising two serums, two moisturizers and an eye cream that are applied in a specified morning and evening routine. Clinically tested across 35 French clinics in collaboration with specialists in plastic surgery, aesthetics and dermatology, this regimen blends the benefits of retinol, hyaluronic acid, vitamin C and tetrahydroxypropyl ethylenediamine (THPE) to deliver revolutionary results in just 90 days, per the company.

Backed by the 35-clinic landmark study, RoC 35 demonstrates that science-driven formulations can visibly rejuvenate skin by nearly a decade, empowering individuals to not only look their best, but feel confident in their skin. The five-product RoC 35 Protocol launched in March 2025 on RoCSkincare.com for $138.99.

Packing RoC 35 with Rejuvenation Power

As stated, the RoC 35 protocol is built on a five-product regimen that includes the Firming Serum Stick and Revive + Glow serums; Firm + Lift and Hydrate + Plump moisturizers; and the Dual Eye Cream. These products feature the star molecules: 

  • Retinol: The gold standard of anti-aging ingredients, stabilized using RoC's proprietary technique, ensuring efficacy over time.
  • Hyaluronic acid: Provides deep hydration and plumping to improve skin elasticity.
  • Vitamin C: Helps brighten the skin, evening out tone and reducing oxidative stress.
  • THPE: Clinically proven to tighten and lift the skin, offering visible firming in record time.

While the first three are well-known by consumers, THPE is perhaps lesser known. It has been described in dermatological research as a molecule that works by contracting the keratinocytes, providing an immediate tightening effect while promoting long-term benefits with regular use. 

Clinical Validation Across 35 French Clinics  

The RoC 35 protocol was developed after rigorous testing in more than 200 participants aged 45 and older. Key highlights from the study include:

  • Skin rejuvenation: Participants reported their skin looked and felt 9.6 years younger on average after 90 days' regimen use.
  • Comprehensive improvement: Thirty key parameters of youthful skin were scrutinized using VISIA’s professional imaging system, resulting in results such as:
    • 98% achieved healthier, more radiant skin tone.
    • 97% found their skin softer, more hydrated and pore appearance minimized.
    • 91% saw significant wrinkle reduction across all areas of the face and neck.
    • 90% noticed firmer, plumper, more elastic and "lifted" skin.
    • 92% reported dramatic improvements around the eyes, including reduced dark circles, crow’s feet and puffiness.

Beyond visible results, the RoC 35 protocol resonated emotionally with participants, with 90% reporting an overall boost in confidence and optimism as their skin's condition visibly improved.

Benoit Chardon, Director of the RoC 35 Study, stated: “Our goal is to simplify skin care, making it easier for consumers to achieve transformative results. By leveraging insights from this extensive research, RoC aims to empower physicians and consumers with the knowledge needed to build a product routine for preventative aging, with the right ingredients at the right time of the day, reinforcing its mission to make science-driven skincare accessible to all.”

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